ADIPOQ 抗体
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北京 101111
Quick Overview for ADIPOQ 抗体 (ABIN7670517)
抗原
See all ADIPOQ 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Adiponectin/Acrp30 Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Rat Adiponectin/Acrp30 protein expressed by E.coli
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亚型
- IgG
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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别名
- Adiponectin/Acrp30
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背景
- Acrp30,Adipoq,Adid,30 kDa adipocyte compLement-reLated protein,Adiponectin d,Adiponectin,C1Q and coLLagen domain containing,Adiponectin,alternately named Adipocyte complement-related protein of 30 kDa (Acrp30),adipoQ,adipose most abundant gene transcript 1 (apM1),and gelatin-binding protein of 28 kDa (GBP28),is an adipocyte-specific,secreted protein with potential roles in glucose and lipid homeostasis. Circulating Adiponectin levels are high,accounting for approximately 0.01 % of total plasma protein. Adiponectin contains a modular structure that includes an N-terminal collagen-like domain followed by a C-terminal globular domain with significant sequence and structural resemblance to the complement factor C1q. Although they share little sequence identity,similar threedimensional structure and certain conserved amino acid residues suggest an evolutionary link between the C1q-like domain of Adiponectin and members of the TNF superfamily. Adiponectin assembles into different complexes including trimers (low molecular weight),hexamers (middle molecular weight),and higher order oligomeric structures (high molecular weight) that may affect biological activity. Adiponectin is induced during adipocyte differentiation and its secretion is stimulated by insulin. Two receptors for Adiponectin,termed AdipoR1 and AdipoR2,have been cloned. Although functionally distinct from G-protein-coupled receptors,the genes encode predicted proteins containing 7 transmembrane domains. AdipoR1 is highly expressed in skeletal muscle,while AdipoR2 is primarily found in hepatic tissues.
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UniProt
- Q8K3R4
抗原
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