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Annexin a1 抗体

The 兔 多克隆 anti-Annexin a1 antibody (ABIN7670503) specifically detects Annexin a1 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7670503
发货至: 中国
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Quick Overview for Annexin a1 抗体 (ABIN7670503)

抗原

See all Annexin a1 (ANXA1) 抗体
Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

适用

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人, 小鼠, 大鼠

宿主

  • 150
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克隆类型

  • 146
  • 108
多克隆

标记

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This Annexin a1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    Annexin A1 Polyclonal Antibody

    纯化方法

    Antigen Affinity Purification

    免疫原

    Recombinant Human Annexin A1 protein expressed by E.coli

    亚型

    IgG
  • 应用备注

    WB 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

    别名

    Annexin A1

    背景

    ANX,Annexin I (lipocortin I),AnnexinA1,AnnexinI,ANX 1,ANX A1,ANXA 1,ANXA1 protein,CalpactinII,Chromobindin9,HGNC:533,Lipocortin 1,lipocortin I,ANX1,LPC1,Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9,Lipocortin I,Phospholipase A2 inhibitory protein,p35,Lipocortin1,LipocortinI,LPC 1,LPC,ANXA,Annexin A,ANXA1,ANX1,LPC1,Annexin 1,Calpactin 2,Chromobindin 9,Annexin-1,Chromobindin-9,p35,Calpactin-2,Annexin A1,Annexin I,Calpactin II,Lipocortin I,Phospholipase A2 Inhibitory Protein,Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells. Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells.Has no effect on unstimulated T cells. Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton.Has high affinity for Ca2+ and can bind up to eight Ca2+ ions. Displays Ca2+-dependent binding to phospholipid membranes. Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca2+-dependent interaction between phagosomes and the actin cytoskeleton.

    分子量

    Calculated MW: 38 kDa

    ObservedMW: 35 kDa

    UniProt

    P04083

    途径

    Hormone Transport
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