Annexin a1 抗体
Quick Overview for Annexin a1 抗体 (ABIN7670503)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Annexin A1 Polyclonal Antibody
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human Annexin A1 protein expressed by E.coli
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亚型
- IgG
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应用备注
- WB 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- Annexin A1
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背景
- ANX,Annexin I (lipocortin I),AnnexinA1,AnnexinI,ANX 1,ANX A1,ANXA 1,ANXA1 protein,CalpactinII,Chromobindin9,HGNC:533,Lipocortin 1,lipocortin I,ANX1,LPC1,Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9,Lipocortin I,Phospholipase A2 inhibitory protein,p35,Lipocortin1,LipocortinI,LPC 1,LPC,ANXA,Annexin A,ANXA1,ANX1,LPC1,Annexin 1,Calpactin 2,Chromobindin 9,Annexin-1,Chromobindin-9,p35,Calpactin-2,Annexin A1,Annexin I,Calpactin II,Lipocortin I,Phospholipase A2 Inhibitory Protein,Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells. Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells.Has no effect on unstimulated T cells. Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton.Has high affinity for Ca2+ and can bind up to eight Ca2+ ions. Displays Ca2+-dependent binding to phospholipid membranes. Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca2+-dependent interaction between phagosomes and the actin cytoskeleton.
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分子量
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Calculated MW: 38 kDa
ObservedMW: 35 kDa
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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