Cathepsin L 抗体
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北京 101111
Quick Overview for Cathepsin L 抗体 (ABIN7670502)
抗原
See all Cathepsin L (CTSL1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Cathepsin L Polyclonal Antibody
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human Cathepsin L protein expressed by Mammalian
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亚型
- IgG
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应用备注
- IHC 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
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别名
- Cathepsin L
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背景
- CATL,CATL1,CTSL,CTSL1,Cathepsin L1,Cathepsin L1 light chain,CathepsinL,FLJ31037,MEP,MGC123162,Major excreted protein,cathepsin L,cb15,ctsl1b,hgg1,The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.
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UniProt
- P07711
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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