TCR V Alpha24-J Alpha18 抗体 (PE)
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北京 101111
Quick Overview for TCR V Alpha24-J Alpha18 抗体 (PE) (ABIN7670257)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE Anti-Human TCR Vα24-Jα18 Antibody[6B11]
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 5 μL/tests
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant
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注意事项
- Please protected from prolonged exposure to light and do not freeze.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months.
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有效期
- 12 months
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- TCR V Alpha24-J Alpha18
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别名
- TCR Valpha24-Jalpha18
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背景
- TCR Vα24-Jα18,TCR Vα24-JαQ,invariant NKT cell,iNKT,Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.
抗原
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