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HLA DQ 抗体 (PE,Cy5)

This anti-HLA DQ antibody is a 小鼠 单克隆 antibody detecting HLA DQ in FACS. Suitable for 人.
产品编号 ABIN7670250
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HLA DQ 抗体 (PE,Cy5) (ABIN7670250)

抗原

HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

适用

  • 48
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宿主

  • 37
  • 13
小鼠

克隆类型

  • 50
单克隆

标记

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This HLA DQ antibody is conjugated to PE,Cy5

应用范围

  • 40
  • 32
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Flow Cytometry (FACS)

克隆位点

1a3
  • 原理

    PE/Cyanine5 Anti-Human HLA-DQ Antibody[1a3]

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    5 μL/tests

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    注意事项

    Please protected from prolonged exposure to light and do not freeze.

    储存条件

    4 °C

    储存方法

    This product can be stored at 2-8°C for 12 months.

    有效期

    12 months
  • 抗原

    HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

    别名

    HLA-DQ

    背景

    Muc-18,MCAM,Mel-CAM,S-endo,HLA-DQ is also known as MHC class II DQ monomorphic antigen. The major histocompatibility complex is composed of two heterodimeric glycoproteins (α and β chains) with apparent molecular weights of 27 and 32 kD. In contrast to other MHC class II molecules, both polypeptide chains of HLA-DQ are polymorphic, with the α chain showing an extremely high degree of polymorphism. HLA-DQ is expressed on B cells in the peripheral blood, and weakly expressed on activated T cells and some monocytes. HLA-DQ is absent on hematopoietic progenitors, resting T cells, erythrocytes, and platelets. HLA-DQ is expressed after HLA-DR and HLA-DP in hematopoietic development. HLA-DQ presents peptide fragments mainly from degraded intravesicular and extracellular proteins to CD4+ T lymphocytes. Specific alleles of HLA-DQ have been linked to the pathogenesis of several autoimmune diseases (including diabetes), both as a susceptibility and resistance factor depending on the particular polymorphism.

    UniProt

    P43121
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