CD19 抗体
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北京 101111
Quick Overview for CD19 抗体 (ABIN7670150)
抗原
See all CD19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AF/LE Purified Anti-Human CD19 Antibody[4G7]
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内毒素水平
- Low Endotoxin
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
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储存液
- Azide free
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注意事项
- avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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有效期
- 12 months
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- CD19 (CD19 Molecule (CD19))
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别名
- CD19
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背景
- CVID,B-lymphocyteantigenCD,B-lymphocyte antigen CD,T-cellsurfaceantigenLeu,Differentiation antigen CD,T-cell surface antigen Leu,B-lymphocytesurfaceantigenB,B-lymphocyte surface antigen B,B4,CVID3,CD19,B-lymphocyteantigenCD19,B-lymphocytesurfaceantigenB4,T-cellsurfaceantigenLeu-12,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12,B4,CVID3,CD19,CD19 Molecule,CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity maturation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR.
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UniProt
- P15391
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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