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CD16 抗体

This anti-CD16 antibody is a 小鼠 单克隆 antibody detecting CD16 in FACS 和 BR. Suitable for 人.
产品编号 ABIN7670149
发货至: 中国

Quick Overview for CD16 抗体 (ABIN7670149)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Blocking Reagent (BR)

克隆位点

3G8
  • 原理

    AF/LE Purified Anti-Human CD16 Antibody[3G8]

    内毒素水平

    Low Endotoxin

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

    储存液

    Azide free

    注意事项

    avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    有效期

    12 months
  • 抗原

    CD16

    别名

    CD16

    背景

    FcγRIII,Fc gamma receptor,Fc gamma receptor 3,CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

    UniProt

    P08637, O75015

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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