CD16 抗体
Quick Overview for CD16 抗体 (ABIN7670149)
抗原
See all CD16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AF/LE Purified Anti-Human CD16 Antibody[3G8]
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内毒素水平
- Low Endotoxin
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
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储存液
- Azide free
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注意事项
- avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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有效期
- 12 months
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- CD16
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别名
- CD16
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背景
- FcγRIII,Fc gamma receptor,Fc gamma receptor 3,CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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UniProt
- P08637, O75015
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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