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CD86 抗体

This anti-CD86 antibody is a 小鼠 单克隆 antibody detecting CD86 in FACS. Suitable for 人.
产品编号 ABIN7670035
发货至: 中国

Quick Overview for CD86 抗体 (ABIN7670035)

抗原

See all CD86 抗体
CD86

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD86 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

IT2-2
  • 原理

    Purified Anti-Human CD86 Antibody[IT2.2]

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    avoid freeze / thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CD86

    别名

    CD86

    背景

    T-lymphocyte activation antigen CD86,Cd86,Activation B7-2 antigen,Early T-cell costimulatory molecule 1,ETC-1,This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

    UniProt

    P42081

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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