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CD3 抗体

This anti-CD3 antibody is a 小鼠 单克隆 antibody detecting CD3 in FACS. Suitable for 人.
产品编号 ABIN7670005
发货至: 中国

Quick Overview for CD3 抗体 (ABIN7670005)

抗原

See all CD3 抗体
CD3

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD3 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

CRIS-7
  • 原理

    Purified Anti-Human CD3E Antibody[CRIS-7]

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    avoid freeze / thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CD3

    别名

    CD3

    背景

    T-cell surface glycoprotein CD3 epsilon chain,CD3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,CD3E,T3E,The CD3ε chain of the CD3-TCR complex is a type I membrane protein that undergoes conformational change following ligation of the TCR-CD3 complex. This conformational change leads to exposure of the proline rich sequence in CD3ε and results in recruitment of Nck. It is expressed by all mature T cells and forms a heteromeric complex with CD3 α/β or γ/δ and ζ chains. It is important in T cell development, and deficiency of this gene has been associated with severe immunodeficiency.

    UniProt

    P07766

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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