CD22 抗体
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北京 101111
Quick Overview for CD22 抗体 (ABIN7669997)
抗原
See all CD22 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Human CD22 Antibody[LL2]
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纯化方法
- >98%, Protein A/G purified
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免疫原
- Recombinant Human CD22 protein
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亚型
- IgG2a, kappa
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应用备注
- FCM 2 μg/mL(1x105-5x105 cells)
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- PBS, pH 7.2. Contains 0.05 % proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze / thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- CD22 (CD22 Molecule (CD22))
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别名
- CD22
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背景
- Lyb,SIGLEC2FLJ,B-cell receptor CD,T-cell surface antigen Leu,sialic acid binding Ig-like lectin,Sialic acid-binding Ig-like lectin,CD22,SIGLEC-2,SIGLEC2,B-cell receptor CD22,BL-CAM,B-lymphocyte cell adhesion molecule,CD22 antigenMGC130020,CD22 Molecule,Lyb-8,sialic acid binding Ig-like lectin 2,Sialic acid-binding Ig-like lectin 2,SIGLEC2FLJ22814,T-cell surface antigen Leu-14,Siglec-2,CD22 Molecule,B cell receptor CD22 precursor,B lymphocyte cell adhesion molecule,BL CAM,BLCAM,CD 22,CD22 antigen,CD22 protein,Lectin 2,Leu14,Lyb8,MGC130020,sialic acid binding Ig like lectin 2,Sialic acid binding immunoglobulin like lectin 2,SIGLEC 2,T cell surface antigen Leu 14,Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or Blymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.
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UniProt
- P20273
抗原
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