CD180 抗体
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北京 101111
Quick Overview for CD180 抗体 (ABIN7669988)
抗原
See all CD180 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Human CD180 Antibody[G28-8]
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze / thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- CD180 (CD180 Molecule (CD180))
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别名
- CD180
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背景
- LY64,RP105,CD180,Ly78,CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
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UniProt
- Q99467
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途径
- Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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