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E2F3 抗体 (AA 381-465)

Cited in 2+ publications. This 兔 多克隆 anti-E2F3 antibody specifically detects E2F3 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN733493
发货至: 中国
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Quick Overview for E2F3 抗体 (AA 381-465) (ABIN733493)

抗原

See all E2F3 抗体
E2F3

适用

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人, 小鼠

宿主

  • 91
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克隆类型

  • 93
  • 3
多克隆

标记

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This E2F3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 381-465

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human E2F3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Yang, Wang, Tang, Bai: "miR-203a suppresses cell proliferation by targeting E2F transcription factor 3 in human gastric cancer." in: Oncology letters, Vol. 14, Issue 6, pp. 7687-7690, (2017) (PubMed).

  • 抗原

    E2F3

    背景

    Synonyms: E2F-3, Transcription factor E2F3, E2F3, KIAA0075

    Background: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity).

    基因ID

    1871

    UniProt

    O00716
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