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Cytokeratin 1 抗体 (AA 141-240)

Name: Cytokeratin 1 抗体 (AA 141-240)
SKU: ABIN733343
Availability: OutOfStock

This anti-Cytokeratin 1 antibody is a 兔多克隆 antibody detecting Cytokeratin 1 in WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc) 和 IHC (fro). Suitable for 人, 大鼠, 小鼠和 Cow. This Primary Antibody has been cited in 6+ publications.

Formalin-fixed and paraffin embedded human liver carcinoma tissue labeled with Anti-P-CK/Cytokeratin AE1+AE3 Polyclonal Antibody, Unconjugated (ABIN733343) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Cytokeratin 1 抗体 (AA 141-240))

IHC

Mouse Bladder lysates probed with Pan Cytokeratin Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. (Cytokeratin 1 抗体 (AA 141-240))

Paraformaldehyde-fixed, paraffin embedded Rat bladder Antigen retrieval by boiling in sodium citrate buffer (pH6. (Cytokeratin 1 抗体 (AA 141-240))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded Human stomach cancer Antigen retrieval by boiling in sodium citrate buffer (pH6. (Cytokeratin 1 抗体 (AA 141-240))

IHC (p)

5 images

(6 references)

产品编号 ABIN733343

发货至: 中国

Datasheet as PDF

Quick Overview for Cytokeratin 1 抗体 (AA 141-240) (ABIN733343)

抗原

See all Cytokeratin 1 (KRT1) 抗体

Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

适用

人, 大鼠, 小鼠, Cow

宿主

兔

克隆类型

多克隆

标记

This Cytokeratin 1 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

抗原表位
20

16

15

13

5

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 141-240

交叉反应

Cow, 人, 小鼠, 大鼠

预测反应

Dog,Pig,Horse,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human pan cytokeratin

亚型

IgG
anti-Keratin 1 (KRT1) antibody
KRT1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Keratin 1 (KRT1) (AA 101-200) antibody
KRT1 适用: 人, 小鼠, 马 WB, FACS, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Keratin 1 (KRT1) (AA 487-644) antibody
KRT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Keratin 1 (KRT1) (AA 189-497) antibody
KRT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Keratin 1 (KRT1) (AA 267-438) antibody
KRT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Keratin 1 (KRT1) (C-Term) antibody
KRT1 适用: 人, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal LHK1 unconjugated

anti-Keratin 1 (KRT1) (AA 415-443) antibody
KRT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18411 unconjugated

anti-Keratin 1 (KRT1) antibody
KRT1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Monoclonal 1C2 unconjugated

anti-Keratin 1 (KRT1) (AA 387-496) antibody
KRT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Keratin 1 (KRT1) (C-Term) antibody
KRT1 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Yang, Li, Qi, Li, Zhou, Qing, Zhang, Gao: "lncRNA H19 is involved in TGF-β1-induced epithelial to mesenchymal transition in bovine epithelial cells through PI3K/AKT Signaling Pathway." in: PeerJ, Vol. 5, pp. e3950, (2017) (PubMed).

Wang, Jin, Fan, Wang, Xing, Niu: "Anti-proliferative activities of finasteride in benign prostate epithelial cells require stromal fibroblasts and c-Jun gene." in: PLoS ONE, Vol. 12, Issue 2, pp. e0172233, (2017) (PubMed).

Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

Li, Wang, Liu, Tu, He, Wang, Han, Li, Li, Tao, Cai: "Identification of apoptotic cells in the thymus of piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus." in: Virus research, Vol. 189, pp. 29-33, (2014) (PubMed).

Li, Jia, Jia, Shi, Li, Ye, Wang, Xiong, Wang, Li: "Enrichment of Oct3/4-positive cells from a human bronchial epithelial cell line." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 121, Issue 7, pp. 612-25, (2013) (PubMed).
抗原

Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

别名

Cytokeratin

背景

Synonyms: pan-cytokeratin, pan-CK, pan CK, P-CK, wide spectrum Cytokeratin, Cytokeratins, [cytokeratins 1, 2,4,5,6,7,8,71,72,75,78].
Background: Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection.