ZFYVE28 抗体 (Biotin)
Quick Overview for ZFYVE28 抗体 (Biotin) (ABIN7662133)
抗原
See all ZFYVE28 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- ZFYVE28 (Zinc Finger FYVE-type containing 28)(LST2/2426), Biotin conjugate
-
产品特性
- ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes. ZFYVE28 is a negative regulator of epidermal growth factor receptor (EGFR) signaling. It acts by promoting EGFR degradation in endosomes when not mono-ubiquitinated. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
免疫原
- Recombinant full-length human ZFYVE28 protein
-
亚型
- IgG2a, kappa
-
-
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) antibody
ZFYVE28 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal LST2-2426 unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 1-887) antibodyZFYVE28 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 131-180) antibodyZFYVE28 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (N-Term) antibodyZFYVE28 适用: 人, 小鼠, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 611-642), (C-Term) antibodyZFYVE28 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 604-633), (C-Term) antibodyZFYVE28 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
Positive Control: PC3 cells. Testis, Brain, Colon, Kidney or Stomach.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
-
Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
有效期
- 24 months
-
-
- ZFYVE28 (Zinc Finger, FYVE Domain Containing 28 (ZFYVE28))
-
别名
- ZFYVE28
-
背景
-
Synonyms: Lateral signaling target protein 2 homolog, LST2, LYST2, Zinc finger FYVE domain-containing protein 28 (ZFYVE28)
Gene Symbol: ZFYVE28
-
分子量
- 96 kDa
-
基因ID
- 57732
-
途径
- EGFR Signaling Pathway
抗原
-
