WT1 抗体 (CF®405S)
Quick Overview for WT1 抗体 (CF®405S) (ABIN7662038)
抗原
See all WT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker), CF405S conjugate
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产品特性
- Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human WT1 protein
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: K562 cells. Wilm's Tumor, mesothelioma or fetal kidney.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- Wilms Tumor 1
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背景
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Synonyms: WT1, AWT1, FWT1, GUD, NPHS4, WAGR, Wilms tumor 1
Gene Symbol: WT1
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分子量
- 47-55 kDa
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基因ID
- 7490
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UniProt
- P19544
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途径
- Tube Formation
抗原
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