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VWF 抗体 (Biotin)

This anti-VWF antibody is a 小鼠 单克隆 antibody detecting VWF in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7662016
发货至: 中国

Quick Overview for VWF 抗体 (Biotin) (ABIN7662016)

抗原

See all VWF 抗体
VWF (Von Willebrand Factor (VWF))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This VWF antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

VWF-2480
  • 原理

    von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker)(VWF/2480), Biotin conjugate

    产品特性

    von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e. g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human VWF protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HUVEC cells. Tonsil.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    VWF (Von Willebrand Factor (VWF))

    别名

    Von Willebrand Factor

    背景

    Synonyms: Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)

    Gene Symbol: VWF

    Tissue Expression: Endothelial cells

    分子量

    250 kDa

    基因ID

    7450

    UniProt

    P04275
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