VWF 抗体 (AA 845-949) (CF®568)
Quick Overview for VWF 抗体 (AA 845-949) (CF®568) (ABIN7661987)
抗原
See all VWF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 845-949
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原理
- von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker)(IIIE2.34), CF568 conjugate
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产品特性
- von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
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免疫原
- Recombinant human vWF fragment spanning aa 845-949
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亚型
- IgG1, kappa
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anti-Von Willebrand Factor (VWF) (AA 1498-1665) antibody
VWF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 269-367) antibodyVWF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VWF-1465 unconjugated
anti-Von Willebrand Factor (VWF) (AA 50-150) antibodyVWF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1304-1452) antibodyVWF 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 2535-2813) antibodyVWF 适用: 人 WB, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) antibodyVWF 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 907CT12-1-9 unconjugated
anti-Von Willebrand Factor (VWF) (AA 351-450) antibodyVWF 适用: 人, 大鼠, 小鼠 FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 49-230) antibodyVWF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 WB, IHC, StM 宿主: 兔 Monoclonal VWF-1859R unconjugated Recombinant Antibody
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistochemistry (formalin-fixed): 0.5-1.0 μg/mL for 30 minutes at RT. Immunoprecipitation: 0.5-1 μg/500 μg protein lysate. Western blot: 0.5-1.0 μg/mL. Flow cytometry: 0.5-1 μg/million cells. Immunofluorescence: 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HUVEC cells. Tonsil.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- VWF (Von Willebrand Factor (VWF))
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别名
- Von Willebrand Factor
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背景
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Synonyms: Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)
Gene Symbol: VWF
Tissue Expression: Endothelial cells
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分子量
- 250 kDa
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基因ID
- 7450
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UniProt
- P04275
抗原
-
