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Vinculin 抗体 (AA 174-322) (CF®647)

Name: Vinculin 抗体 (AA 174-322) (CF®647)
SKU: ABIN7661956
Availability: OutOfStock

This anti-Vinculin antibody is a 小鼠单克隆 antibody detecting Vinculin in IHC 和 IHC (fp). Suitable for 人和小鼠.

产品编号 ABIN7661956

发货至: 中国

Quick Overview for Vinculin 抗体 (AA 174-322) (CF®647) (ABIN7661956)

抗原

See all Vinculin (VCL) 抗体

Vinculin (VCL)

适用

人, 小鼠

宿主

小鼠

克隆类型

单克隆

标记

This Vinculin antibody is conjugated to CF®647

应用范围

Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

VCL-2573

Discover our top product VCL Primary Antibody

抗原表位
25

16

9

7

6

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 174-322

原理

Vinculin (Marker of Age-related Macular Degeneration)(VCL/2573), CF647 conjugate

产品特性

Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including talin and alpha-actinin each contain actin binding sites. Reportedly, vinculin is a potential plasma biomarker for Age-related Macular Degeneration (AMD). The early detection of AMD using novel plasma biomarkers with genetic modeling may enable timely treatment and vision preservation in the elderly. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

免疫原

Recombinant fragment (around aa 174-322) of human Vinculin (VCL) protein

亚型

IgG1, kappa
anti-Vinculin (VCL) (AA 1-1066) antibody
VCL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C6-1B5 unconjugated

anti-Vinculin (VCL) (AA 879-1064) antibody
VCL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) (AA 903-937) antibody
VCL 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55983 unconjugated

anti-Vinculin (VCL) (AA 1020-1134) antibody
VCL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) (AA 634-668) antibody
VCL 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55982 unconjugated

anti-Vinculin (VCL) (AA 1-1066) antibody
VCL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F8-1D4 unconjugated

anti-Vinculin (VCL) (AA 174-322) antibody
VCL 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VCL-2575 unconjugated

anti-Vinculin (VCL) (AA 174-322) antibody
VCL 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VCL-2572 unconjugated

anti-Vinculin (VCL) (AA 767-1066) antibody
VCL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) antibody
VCL 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

Positive Control: Human Bladder and Testis.

限制

仅限研究用
状态

Liquid

浓度

0.1 mg/mL

缓冲液

PBS, 0.1 % BSA, 0.05 % azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Protect from light

储存条件

4 °C

储存方法

Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light

有效期

24 months
抗原

Vinculin (VCL)

别名

Vinculin

背景

Synonyms: CMD1W, CMH15, Epididymis luminal protein 114, HEL114, Metavinculin, MV, MVCL, VCL, VINC
Gene Symbol: VCL

分子量

117 kDa

基因ID

7414

UniProt

P18206

途径

Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2