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VCAM1 抗体 (CF®740)

This anti-VCAM1 antibody is a 小鼠 单克隆 antibody detecting VCAM1 in FACS, IF 和 Func. Suitable for 人.
产品编号 ABIN7661831
发货至: 中国

Quick Overview for VCAM1 抗体 (CF®740) (ABIN7661831)

抗原

See all VCAM1 抗体
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This VCAM1 antibody is conjugated to CF®740

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

B-K9
  • 原理

    CD106 / VCAM1(B-K9), CF740 conjugate

    产品特性

    CD106 (also known as vascular cell adhesion molecule-1, or VCAM-1) is a member of the Ig superfamily of adhesion molecules. It is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte beta-1 integrin VLA-4 and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Activated human umbilical vein endothelial cells (HUVEC)

    亚型

    IgG1, kappa
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: Human placenta or tonsil

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    别名

    CD106

    背景

    Synonyms: CD106, VCAM-1, Vascular Cell Adhesion Molecule 1, VCAM1, INCAM-100

    Gene Symbol: VCAM1

    Tissue Expression: Endothelial cells

    分子量

    ~110 kDa

    基因ID

    7412

    UniProt

    P19320

    途径

    Carbohydrate Homeostasis
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