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Recombinant VTCN1 抗体 (CF®647)

This anti-VTCN1 antibody is a 兔 单克隆 antibody detecting VTCN1 in IHC, FACS, IF 和 IHC (fp). Suitable for 人.
产品编号 ABIN7661775
发货至: 中国

Quick Overview for Recombinant VTCN1 抗体 (CF®647) (ABIN7661775)

抗原

See all VTCN1 抗体
VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This VTCN1 antibody is conjugated to CF®647

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

B7H4-2652R
  • 原理

    B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF647 conjugate

    产品特性

    B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human B7-H4 protein fragment

    亚型

    IgG
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. ELISA: 2-4 μg/m for coating order Ab without BSA. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: HeLa or MCF-7 Cells. Ovary, Pancreas, Placenta or Spleen.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

    别名

    B7-H4

    背景

    Synonyms: B7-H4, B7H4, B7X, B7 family member, H4, B7 homolog 4, B7 superfamily member 1, B7S1, B7 family member H4

    Gene Symbol: VTCN1

    分子量

    35 kDa

    基因ID

    79679

    UniProt

    Q7Z7D3
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