MYB 抗体 (AA 119-135) (CF®740)
Quick Overview for MYB 抗体 (AA 119-135) (CF®740) (ABIN7661767)
抗原
See all MYB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 119-135
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原理
- c-Myb(MYB286), CF740 conjugate
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产品特性
- The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH
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亚型
- IgG1, kappa
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anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 281-294) antibody
Verified MYB 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (C-Term) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 1-640) antibodyMYB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (C-Term) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (pSer532) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 305-558) antibodyMYB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 1-50) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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别名
- c-Myb
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背景
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Synonyms: c-myb_CDS, efg, ONCOGENE AMV, Oncogene MYB, Proto-oncogene c-Myb, Transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog
Gene Symbol: MYB
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分子量
- 75 kDa
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基因ID
- 4602
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UniProt
- P01104
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途径
- Chromatin Binding, Positive Regulation of Immune Effector Process
抗原
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