Uroplakin 3A 抗体 (AA 260-279) (CF®740)
Quick Overview for Uroplakin 3A 抗体 (AA 260-279) (CF®740) (ABIN7661693)
抗原
See all Uroplakin 3A (UPK3A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 260-279
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原理
- UPK3A (Uroplakin 3A)(Rabbit PAb), CF740 conjugate
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产品特性
- Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A
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亚型
- IgG
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anti-Uroplakin 3A (UPK3A) (AA 15-212) antibody
UPK3A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uroplakin 3A (UPK3A) (AA 19-207) antibodyUPK3A 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uroplakin 3A (UPK3A) (AA 15-211) antibodyUPK3A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uroplakin 3A (UPK3A) antibodyUPK3A 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uroplakin 3A (UPK3A) (AA 19-207) antibodyUPK3A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uroplakin 3A (UPK3A) (AA 260-279) antibodyUPK3A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HEK293 cells or bladder carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Uroplakin 3A (UPK3A)
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别名
- UPK3A
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背景
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Synonyms: UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A
Gene Symbol: UPK3A
Tissue Expression: Urothelial cells
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分子量
- ~30 kDa
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基因ID
- 7380
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UniProt
- O75631
抗原
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