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Recombinant Ubiquitin 抗体 (AA 1-119)

Name: Recombinant Ubiquitin 抗体 (AA 1-119)
SKU: ABIN7661594
Availability: OutOfStock

This anti-Ubiquitin antibody is a 兔单克隆 antibody detecting Ubiquitin in IHC 和 IHC (fp). Suitable for 人.

产品编号 ABIN7661594

发货至: 中国

Quick Overview for Recombinant Ubiquitin 抗体 (AA 1-119) (ABIN7661594)

抗原

See all Ubiquitin (Ub) 抗体

Ubiquitin (Ub)

抗体类型

Recombinant Antibody

适用

人

宿主

兔

克隆类型

单克隆

标记

This Ubiquitin antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

UBB-3143R

Discover our top product Ub Primary Antibody

抗原表位
29

18

8

8

7

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 1-119

原理

Ubiquitin (Autophagy Marker)(UBB/3143R)

产品特性

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e. g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

免疫原

Recombinant fragment of human Ubiquitin protein (around aa 1-119)

亚型

IgG
anti-Ubiquitin (Ub) antibody
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin (Ub) (AA 1-229) antibody
Ub 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, 马 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin (Ub) (AA 1-229) antibody
Ub 适用: 人, 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal D2 unconjugated

anti-Ubiquitin (Ub) (acLys27) antibody
Ub 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin (Ub) antibody (HRP)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal HRP

anti-Ubiquitin (Ub) antibody (FITC)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal FITC

anti-Ubiquitin (Ub) antibody (Biotin)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Biotin

anti-Ubiquitin (Ub) antibody (PE)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal PE

anti-Ubiquitin (Ub) antibody (APC)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal APC

anti-Ubiquitin (Ub) antibody (PerCP)
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal PerCP

应用备注

Optimal working dilution should be determined by the investigator.

说明

Positive Control: HeLa or Jurkat cells. Alzheimer Brain.

限制

仅限研究用
状态

Liquid

浓度

0.2 mg/mL

缓冲液

PBS, 0.05 % BSA, 0.05 % azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light

有效期

24 months
抗原

Ubiquitin (Ub)

别名

Ubiquitin

背景

Synonyms: Epididymis secretory protein Li 50, Polyubiquitin B, RPS27A, UBA52, UBA80, UBB, UBC, UBCEP1, UBCEP2
Gene Symbol: UBB

分子量

9 kDa

基因ID

7314

UniProt

P62979, P62987, P62988

途径

Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway