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TTR 抗体 (CF®594)

This anti-TTR antibody is a 小鼠 单克隆 antibody detecting TTR in WB. Suitable for 人.
产品编号 ABIN7661068
发货至: 中国

Quick Overview for TTR 抗体 (CF®594) (ABIN7661068)

抗原

See all TTR 抗体
TTR (Transthyretin (TTR))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TTR antibody is conjugated to CF®594

应用范围

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Western Blotting (WB)

克隆位点

CPTC-TTR-1
  • 原理

    Transthyretin (Prealbumin)(CPTC-TTR-1), CF594 conjugate

    产品特性

    Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human full-length protein

    亚型

    IgG2a, kappa
  • 应用备注

    ELISA: For coating, order Ab without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

    说明

    Positive Control: HepG2, Pancreas and liver.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    TTR (Transthyretin (TTR))

    别名

    Transthyretin

    背景

    Synonyms: Transthyretin, PALB, HsT2651, prealbumin, amyloidosis type 1, ATTR, TBPA, CTS, CTS1, carpal tunnel syndrome 1, thyroxine-binding prealbumin, prealbumin, HEL111, TTR protein, Epididymis luminal protein 111, prealbumin thyroxine binding, senile systemic amyloidosis antibody

    Gene Symbol: TTR

    分子量

    15 kDa

    基因ID

    7276

    UniProt

    P02766

    途径

    Hormone Transport
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