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Recombinant Transferrin Receptor 抗体 (AA 94-212) (CF®405S)

This anti-Transferrin Receptor antibody is a 兔 单克隆 antibody detecting Transferrin Receptor in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7661022
发货至: 中国

Quick Overview for Recombinant Transferrin Receptor 抗体 (AA 94-212) (CF®405S) (ABIN7661022)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

抗体类型

Recombinant Antibody

适用

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宿主

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  • 1
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克隆类型

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  • 4
单克隆

标记

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This Transferrin Receptor antibody is conjugated to CF®405S

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

TFRC-2898R
  • 抗原表位

    • 31
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    AA 94-212

    原理

    CD71 / Transferrin Receptor (TFRC) (Extracellular Domain)(TFRC/2898R), CF405S conjugate

    产品特性

    Recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human extracellular TFRC protein fragment (aa94-212)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Jurkat, HeLa, MCF-7 or K562 cells. Human placenta or Bone Marrow.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    CD71

    背景

    Synonyms: Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

    Tissue Expression: Microvascular endothelial cells

    分子量

    85-95 kDa (monomer), 190 kDa (dimer)

    基因ID

    7037

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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