TIMP1 抗体 (AA 72-82) (CF®647)
Quick Overview for TIMP1 抗体 (AA 72-82) (CF®647) (ABIN7660839)
抗原
See all TIMP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 72-82
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原理
- TIMP1 (Marker of Lymph Node Metastasis)(2A5), CF647 conjugate
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产品特性
- TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- A synthetic peptide (aa 72-82) of human TIMP1 protein (FQALGDAADIR)
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亚型
- IgG1, kappa
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anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 103-207) antibody
TIMP1 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 157-188), (C-Term) antibodyTIMP1 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB14602 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 41-70), (N-Term) antibodyTIMP1 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB15494 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-207) antibodyTIMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibodyTIMP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibodyTIMP1 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 8B4E9 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-169) antibodyTIMP1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibodyTIMP1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 131-207) antibodyTIMP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-217) antibodyTIMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: Use Ab at 2-4 μg/mL for coating, Order Ab without BSA, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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说明
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Positive Control: 293 cells. Colon Carcinoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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别名
- TIMP1
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背景
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Synonyms: Collagenase inhibitor, EPO, Erythroid-Potentiating Activity (EPA), Fibroblast collagenase inhibitor, Human Collagenase Inhibitor (HCI), Metalloproteinase inhibitor 1, Tissue Inhibitor of Metalloproteinase 1 (TIMP1)
Gene Symbol: TIMP1
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分子量
- 23 kDa
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基因ID
- 7076
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UniProt
- P01033
抗原
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