Recombinant Thyroperoxidase 抗体 (AA 685-804)
Quick Overview for Recombinant Thyroperoxidase 抗体 (AA 685-804) (ABIN7660817)
抗原
See all Thyroperoxidase (TPO) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 685-804
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原理
- TPO (Thyroid Peroxidase) (Thyroid Marker)(TPO/3813R)
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产品特性
- Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human TPO (around aa 685-804)
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亚型
- IgG
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anti-Thyroid Peroxidase (TPO) (AA 1-933) antibody
TPO 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 672-779) antibodyTPO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Thyroid Peroxidase (TPO) (AA 111-210) antibodyTPO 适用: 人, 大鼠 WB, ELISA, ICC, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (C-Term) antibodyVerified TPO 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 636-832) antibodyTPO 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 19-846) antibodyTPO 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 107-276) antibodyTPO 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (Internal Region) antibody (Biotin)Verified TPO 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal Biotin
anti-Thyroid Peroxidase (TPO) (C-Term) antibody (Biotin)Verified TPO 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal Biotin
anti-Thyroid Peroxidase (TPO) (AA 1-933) antibodyTPO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Thyroid Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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别名
- Thyroid Peroxidase
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背景
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Synonyms: MSA, TDH2A, Thyroid microsomal antigen, Thyroid peroxidase, Thyroperoxidase, TPO, TPX
Gene Symbol: TPO
Tissue Expression: Thyroid
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分子量
- 100 kDa
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基因ID
- 7173
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UniProt
- P07202
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途径
- Thyroid Hormone Synthesis
抗原
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