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Recombinant Thyroglobulin 抗体 (CF®568)

This anti-Thyroglobulin antibody is a 兔 单克隆 antibody detecting Thyroglobulin in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7660765
发货至: 中国

Quick Overview for Recombinant Thyroglobulin 抗体 (CF®568) (ABIN7660765)

抗原

See all Thyroglobulin (TG) 抗体
Thyroglobulin (TG)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Thyroglobulin antibody is conjugated to CF®568

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

TGB-1970R
  • 原理

    Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), CF568 conjugate

    产品特性

    Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human Thyroglobulin protein

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Thyroid

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Thyroglobulin (TG)

    别名

    Thyroglobulin

    背景

    Synonyms: AITD3, hTG, TDH3, Tg, Tgn

    Gene Symbol: TG

    Tissue Expression: Thyroid

    分子量

    660 kDa (Dimeric Form)

    基因ID

    7038

    UniProt

    P01266

    途径

    Thyroid Hormone Synthesis
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