Thrombomodulin 抗体 (AA 69-194) (CF®740)
Quick Overview for Thrombomodulin 抗体 (AA 69-194) (CF®740) (ABIN7660701)
抗原
See all Thrombomodulin (THBD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 69-194
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原理
- Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1591), CF740 conjugate
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产品特性
- This antibody recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi's sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human Thrombomodulin protein fragment (aa69-194)
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亚型
- IgG2b, kappa
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anti-Thrombomodulin (THBD) (AA 69-194) antibody
THBD 适用: 人 WB, IHC, ELISA, Coat, ISt, StM 宿主: 小鼠 Monoclonal THBD-1591 unconjugated
anti-Thrombomodulin (THBD) (AA 200-500) antibodyTHBD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 69-194) antibodyTHBD 适用: 人 IHC, ELISA, Coat, ISt, StM 宿主: 小鼠 Monoclonal rTHBD-1591 unconjugated Recombinant Antibody
anti-Thrombomodulin (THBD) (AA 69-194) antibodyTHBD 适用: 人 IHC, ELISA, Coat, ISt, StM 宿主: 小鼠 Monoclonal THBD-1782 unconjugated
anti-Thrombomodulin (THBD) (C-Term) antibodyTHBD 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (C-Term) antibodyTHBD 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 297-505) antibodyTHBD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2C6C3 unconjugated
anti-Thrombomodulin (THBD) (AA 31-167) antibodyTHBD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 324-480) antibodyTHBD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 92-126) antibodyTHBD 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB56919 unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. ELISA: 2-4 μg/mL for coating order Ab without BSA. Immunofluorescence: 0.5-1 μg/mL. Immunohistology (formalin) 1-2 μg/mL. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris buffer with1 mM EDTA. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: THP1 Cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Thrombomodulin (THBD)
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别名
- CD141
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背景
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Synonyms: AHUS6, BDCA3, CD141, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin (TM)
Gene Symbol: THBD
Tissue Expression: Endothelial cells
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分子量
- 100 kDa
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基因ID
- 7056
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UniProt
- P07204
抗原
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