TGF-beta 抗体 (CF®488A)
Quick Overview for TGF-beta 抗体 (CF®488A) (ABIN7660692)
抗原
See all TGF-beta (TGFb) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TGF-beta (Transforming Growth Factor beta)(TGFB/510), CF488A conjugate
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产品特性
- This MAb recognizes TGF beta 1, 2 and 3. TGFs inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Most breast lesions, benign and malignant, involve abnormal proliferation and altered architecture of stromal and/or epithelial elements.
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免疫原
- Full length recombinant human TGF-beta2 protein
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亚型
- IgG1, kappa
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Ovarian carcinoma, lung tumor or skin. PC-3 cell line. Eahy926 cells.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- TGF-beta (TGFb)
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别名
- TGF-Beta
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背景
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Synonyms: ARVD, BSC 1 cell growth inhibitor, CED, Cetermin, Diaphyseal dysplasia 1 (DPD1), Glioblastoma derived T cell suppressor factor (G TSF), Latency-associated peptide (LAP), Polyergin, Transforming growth factor beta 1 (TGF beta1 or TGFB1), TGF beta2 (TGFB2), TGF beta3 (TGFB3), TGFbeta (TGFB)
Gene Symbol: TFGB
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分子量
- ~13 kDa
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基因ID
- 7040, 7042, 7043
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UniProt
- P01137, P10600, P61812
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途径
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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