STAR 抗体 (AA 39-108) (CF®594)
Quick Overview for STAR 抗体 (AA 39-108) (CF®594) (ABIN7660413)
抗原
See all STAR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 39-108
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原理
- StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) (STAR/2140), CF594 conjugate
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产品特性
- Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 39-108) of human STAR protein
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亚型
- IgG2b, kappa
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anti-Steroidogenic Acute Regulatory Protein (STAR) (AA 81-180) antibody
STAR 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 5F9 unconjugated
anti-Steroidogenic Acute Regulatory Protein (STAR) (AA 39-108) antibodySTAR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal STAR-2154 unconjugated
anti-Steroidogenic Acute Regulatory Protein (STAR) (AA 101-200) antibodySTAR 适用: 人, 小鼠, 大鼠, 绵羊, 小鸡 WB, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Steroidogenic Acute Regulatory Protein (STAR) (AA 1-285) antibodySTAR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Steroidogenic Acute Regulatory Protein (STAR) (AA 39-108) antibodySTAR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal STAR-2140 unconjugated
anti-Steroidogenic Acute Regulatory Protein (STAR) antibodySTAR 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Steroidogenic Acute Regulatory Protein (STAR) antibodySTAR 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-740R unconjugated Recombinant Antibody
anti-Steroidogenic Acute Regulatory Protein (STAR) (AA 64-285) antibodySTAR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Steroidogenic Acute Regulatory Protein (STAR) (AA 64-285) antibodySTAR 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Steroidogenic Acute Regulatory Protein (STAR) (AA 1-291) antibodySTAR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: K-562 cells. Adrenal or Testicular Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- STAR (Steroidogenic Acute Regulatory Protein (STAR))
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别名
- StAR
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背景
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Synonyms: Cholesterol trafficker, Luteinizing hormone induced protein, Mitochondrial steroid acute regulatory protein, StAR, StAR related lipid transfer (START) domain containing 1, StARD1, START domain-containing protein 1, Steroid acute regulatory protein, Steroidogenic acute regulator (STAR), Steroidogenic acute regulatory protein mitochondrial
Gene Symbol: STAR
Tissue Expression: Adrenal gland|Ovary|Testis
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分子量
- ~30 kDa
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基因ID
- 6770
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UniProt
- P49675
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途径
- Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
抗原
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