Recombinant SOX9 抗体 (CF®640R)
Quick Overview for Recombinant SOX9 抗体 (CF®640R) (ABIN7660331)
抗原
See all SOX9 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
 - SOX9 / SRY-box 9(SOX9/2287R), CF640R conjugate
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产品特性
 - The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
 - Recombinant human full-length SOX9 protein
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亚型
 - IgG
 
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应用备注
 - For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Human Skin Hair follicles.
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 0.1 mg/mL
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缓冲液
 - PBS, 0.1 % BSA, 0.05 % azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from light
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储存条件
 - 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
 - 24 months
 
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- SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
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别名
 - SOX9
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背景
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Synonyms: CMD 1, campomelic dysplasia autosomal sex reversal, SRA1, SRXX2, SRXY10, SRY (sex determining region Y) box 9, SRY related HMG box gene 9, Transcription factor SOX 9
Gene Symbol: SOX9
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分子量
 - 56 kDa
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基因ID
 - 6662
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UniProt
 - P48436
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途径
 - EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
 
抗原
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