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Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (CF®568)

This anti- antibody is a 兔 单克隆 antibody detecting in WB, IHC 和 IHC (fp). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7660183
发货至: 中国

Quick Overview for Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (CF®568) (ABIN7660183)

抗原

See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体
Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

抗体类型

Recombinant Antibody

适用

  • 126
  • 35
  • 33
  • 1
人, 小鼠, 大鼠

宿主

  • 68
  • 58

克隆类型

  • 115
  • 11
单克隆

标记

  • 47
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
CF®568

应用范围

  • 123
  • 86
  • 80
  • 76
  • 42
  • 20
  • 14
  • 7
  • 5
  • 5
  • 3
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

SPTBN2-2979R
  • 抗原表位

    • 113
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-475

    原理

    Spectrin beta III (SPTBN2)(SPTBN2/2979R), CF568 conjugate

    产品特性

    Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (around aa356-475) of human SPTBN2 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa cells. Pancreas or Liver.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

    别名

    Spectrin Beta-III

    背景

    Synonyms: Beta III spectrin, SCA5, Spectrin beta chain brain 2, Spectrin beta non-erythrocytic 2, Spectrin non-erythroid beta chain 2, Spinocerebellar ataxia 5, SPTBN2

    Gene Symbol: SPTBN2

    分子量

    246 kDa

    基因ID

    6712

    UniProt

    O15020

    途径

    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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