Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (CF®405S)
Quick Overview for Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (CF®405S) (ABIN7660164)
抗原
See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 356-475
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原理
- Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF405S conjugate
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产品特性
- Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta I (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin beta III is highly homologous to both spectrin beta I and spectrin beta II. Spectrin beta III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human SPTBN2 fragment (aa356-475)
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亚型
- IgG
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anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) antibody
SPTBN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal SPTBN2-2894R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, IHC, IF, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTBN2-1778 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人, 小鼠, 大鼠 WB, FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal SPTBN2-1584 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal SPTBN2-1583 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, IF, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTBN2-1582 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人, 小鼠, 大鼠 WB, IHC, StM 宿主: 兔 Monoclonal SPTBN2-2979R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, IF, StM 宿主: 兔 Monoclonal SPTBN2-2887R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, IHC, ELISA, Coat 宿主: 小鼠 Monoclonal rSPTBN2-1778 unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 643-720) antibodySPTBN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D9 unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. ELISA: 2-4 μg/m for coating order Ab without BSA. Immunohistology (formalin): 0.5-1.0 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Western blotting 0.5-1.0 μg/mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HeLa cells. Pancreas or Liver.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
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别名
- Spectrin Beta-III
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背景
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Synonyms: Beta III spectrin, SCA5, Spectrin beta chain brain 2, Spectrin beta non-erythrocytic 2, Spectrin non-erythroid beta chain 2, Spinocerebellar ataxia 5, SPTBN2
Gene Symbol: SPTBN2
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分子量
- 246 kDa
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基因ID
- 6712
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UniProt
- O15020
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途径
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
抗原
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