SPTBN1 抗体 (CF®594)
Quick Overview for SPTBN1 抗体 (CF®594) (ABIN7660158)
抗原
See all SPTBN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Spectrin beta I (SPTB)(RG/26), CF594 conjugate
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产品特性
- Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Red cell membranes
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亚型
- IgG2a, kappa
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anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) (AA 2096-2256) antibody
SPTBN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) (N-Term) antibodySPTBN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) (AA 2063-2097) antibodySPTBN1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB54579 unconjugated
anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) antibodySPTBN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) (AA 2100-2200) antibodySPTBN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Jurkat whole cell lysate (WB). Human colon carcinoma tissue (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))
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别名
- Spectrin beta I
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背景
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Synonyms: beta-I spectrin, EL3, erythrocyte, HS2, SPTB1, HSPTB1, membrane cytoskeletal protein, spectrin beta (erythrocytic)
Gene Symbol: SPTB
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分子量
- 246 kDa
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基因ID
- 6710
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UniProt
- O15020
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途径
- Regulation of Actin Filament Polymerization, Protein targeting to Nucleus
抗原
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