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SELPLG 抗体

This anti-SELPLG antibody is a 小鼠 单克隆 antibody detecting SELPLG in . Suitable for 人.
产品编号 ABIN7659764
发货至: 中国

Quick Overview for SELPLG 抗体 (ABIN7659764)

抗原

See all SELPLG 抗体
SELPLG (Selectin P Ligand (SELPLG))

适用

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宿主

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小鼠

克隆类型

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单克隆

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This SELPLG antibody is un-conjugated

应用范围

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克隆位点

PSGL1-1567
  • 原理

    CD162 (Selectin P Ligand)(PSGL1/1567)

    产品特性

    CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human SELPLG (CD162) protein

    亚型

    IgM, kappa
  • 应用备注

    For coating for ELISA, order Ab without BSA. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    说明

    Positive Control: Jurkat cells. Tonsil.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    SELPLG (Selectin P Ligand (SELPLG))

    别名

    CD162

    背景

    Synonyms: CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein ligand 1, PSGL1, Selectin P ligand, SELPLG

    Gene Symbol: SELPLG

    Tissue Expression: Myeloid cells|T-cells

    分子量

    43-120 kDa

    基因ID

    6404

    UniProt

    Q14242
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