s100a4 抗体
Quick Overview for s100a4 抗体 (ABIN7659720)
抗原
See all s100a4 (S100A4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- S100A4 / Metastasin / Calvasculin (Marker of Tumor Metastasis)(CPTC-S100A4-3)
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产品特性
- S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100A4 has been implicated in the progression and prognosis of several forms of human cancer, e. g. breast, colorectal, gastric, pancreatic and bladder cancer, SCLC and oesophageal squamous cell carcinoma, among others. Poor prognosis associated with high S100A4 expression is accompanied by clear signs of disease progression, e. g. high histological and clinical grades and involvement of lymph nodes. Also indicative of poor prognosis is high S100A4 expression coupled with reduced E-cadherin expression in pancreatic, oral squamous cell carcinoma and in melanoma. S100A4 expression is inversely related with expression of metastasis suppressor nm23 and with prognosis of breast cancer. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human S100A4 full length protein
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亚型
- IgG2c, kappa
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anti-S100 Calcium Binding Protein A4 (S100A4) (AA 15-101) antibody
S100A4 适用: 人, 小鼠, 大鼠, 兔 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A4 (S100A4) (AA 1-101) antibodyS100A4 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 1F12-1G7 unconjugated
anti-S100 Calcium Binding Protein A4 (S100A4) (AA 1-200) antibodyS100A4 适用: 人, 小鼠 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal rS100A4-1481 unconjugated Recombinant Antibody
anti-S100 Calcium Binding Protein A4 (S100A4) (AA 1-200) antibodyS100A4 适用: 人, 小鼠 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal S100A4-1481 unconjugated
anti-S100 Calcium Binding Protein A4 (S100A4) antibodyS100A4 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal CPTC-S100A4-3 unconjugated
anti-S100 Calcium Binding Protein A4 (S100A4) (AA 1-200) antibodyS100A4 适用: 人, 小鼠 WB, IHC, IF, FACS, StM 宿主: 兔 Monoclonal S100A4-2750R unconjugated Recombinant Antibody
anti-S100 Calcium Binding Protein A4 (S100A4) (C-Term) antibodyVerified S100A4 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A4 (S100A4) antibodyS100A4 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal S100A4-1481 unconjugated
anti-S100 Calcium Binding Protein A4 (S100A4) antibodyS100A4 适用: 人, 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal 3A6H9 unconjugated
anti-S100 Calcium Binding Protein A4 (S100A4) (C-Term) antibodyS100A4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: 1-2 μg/million cells, Immunofluorescence: 1-2 μg/mL, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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说明
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Positive Control: T98G, HeLa, A549 or A375 cells. Placenta, small intestine.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
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别名
- Calvasculin
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背景
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Synonyms: S100 calcium-binding protein A4, Calvasculin, CAPL, Fibroblast specific protein 1 (FSP1), Leukemia multidrug resistance associated protein, Malignant transformation suppression 1 (MTS1), Metastasin, Placental calcium-binding protein
Gene Symbol: S100A4
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分子量
- 12 kDa
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基因ID
- 6275
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UniProt
- P26447
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途径
- S100 Proteins
抗原
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