S100A1 抗体
Quick Overview for S100A1 抗体 (ABIN7659682)
抗原
See all S100A1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            原理
- S100A1 (Melanoma Marker)(S100A1/1942)
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                                            产品特性
- The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19, 000, full-length human proteins. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the alpha-chain (i. e. in S-100A and S-100B) but not on the beta-chain of S-100 (i. e. in S-100B). This antibody can be used to localize S-100A in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, epithelial and myoepithelial cells of the breast, salivary and sweat glands. Neoplasms derived from these cells also express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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                                            免疫原
- Recombinant human full-length S100A1 protein
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                                            亚型
- IgG1, kappa
 
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                                            应用备注
- Optimal working dilution should be determined by the investigator.
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                                            说明
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                        Positive Control: A431 or HT-29 Cells. Brain or Melanoma 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 0.2 mg/mL
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                                            缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C
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                                            储存方法
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                        Stable at room temperature or 37°C for 7 days. Store at 2 to 8°C. Protect fluorescent conjugates from light 
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                                            有效期
- 24 months
 
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    - S100A1 (S100 Calcium Binding Protein A1 (S100A1))
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                                            别名
- S100A1
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                                            背景
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                        Synonyms: Bpb, NEF, S100-A1, S100 Alpha Chain, S100 Beta Chain, S100 Calcium Binding Protein A1, S100 Calcium Binding Protein B, S100 Calcium Binding Protein Beta Neural Gene Symbol: S100A1 
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                                            分子量
- 10-12 kDa
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                                            基因ID
- 6271
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                                            UniProt
- P23297
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                                            途径
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
 抗原
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