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S100A1 抗体 (Biotin)

This anti-S100A1 antibody is a 小鼠 单克隆 antibody detecting S100A1 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7659681
发货至: 中国

Quick Overview for S100A1 抗体 (Biotin) (ABIN7659681)

抗原

See all S100A1 抗体
S100A1 (S100 Calcium Binding Protein A1 (S100A1))

适用

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小鼠

克隆类型

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单克隆

标记

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This S100A1 antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

S100A1-1942
  • 原理

    S100A1 (Melanoma Marker)(S100A1/1942), Biotin conjugate

    产品特性

    The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19, 000, full-length human proteins. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the alpha-chain (i. e. in S-100A and S-100B) but not on the beta-chain of S-100 (i. e. in S-100B). This antibody can be used to localize S-100A in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, epithelial and myoepithelial cells of the breast, salivary and sweat glands. Neoplasms derived from these cells also express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human full-length S100A1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: A431 or HT-29 Cells. Brain or Melanoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    S100A1 (S100 Calcium Binding Protein A1 (S100A1))

    别名

    S100A1

    背景

    Synonyms: Bpb, NEF, S100-A1, S100 Alpha Chain, S100 Beta Chain, S100 Calcium Binding Protein A1, S100 Calcium Binding Protein B, S100 Calcium Binding Protein Beta Neural

    Gene Symbol: S100A1

    分子量

    10-12 kDa

    基因ID

    6271

    UniProt

    P23297

    途径

    Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
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