Prolactin Receptor 抗体 (CF®740)
Quick Overview for Prolactin Receptor 抗体 (CF®740) (ABIN7659177)
抗原
See all Prolactin Receptor (PRLR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Prolactin Receptor(PRLR/742), CF740 conjugate
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产品特性
- This antibody recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human prolactin receptor
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亚型
- IgG1, kappa
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology formalin-fixed 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Testicular Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Prolactin Receptor (PRLR)
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别名
- Prolactin Receptor
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背景
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Synonyms: CPRLP|hPRL receptor|hPRLrI|Lactogen receptor|OPR|Pr-1|Pr-3|PRL-R|Prolactin receptor delta 7/11|RATPRLR|Secreted prolactin binding protein|Truncated testis-specific box 1-C prolactin receptor
Gene Symbol: PRLR
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分子量
- 70 kDa
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基因ID
- 5618
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UniProt
- P16471
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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