PDCD1LG2 抗体 (AA 27-220) (CF®488A)
Quick Overview for PDCD1LG2 抗体 (AA 27-220) (CF®488A) (ABIN7658998)
抗原
See all PDCD1LG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 27-220
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原理
- PD-L2 / PDCD1LG2 / CD273(PDL2/1850), CF488A conjugate
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产品特性
- Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 27-220) of human PD-L2 protein
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亚型
- IgG1, kappa
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anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 21-118) antibody
PDCD1LG2 适用: 人 WB, FACS, IHC, ELISA, IP, IF 宿主: 小鼠 Monoclonal 7F11D11 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 27-220) antibodyPDCD1LG2 适用: 人 WB, FACS, ELISA, IF, Coat 宿主: 小鼠 Monoclonal PDL2-2676 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 33-236) antibodyPDCD1LG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 36-219) antibodyPDCD1LG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) antibodyPDCD1LG2 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal 24F-10C12 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) antibody (PE)PDCD1LG2 适用: 人 FACS 宿主: 小鼠 Monoclonal 24F-10C12 PE
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 21-268) antibodyPDCD1LG2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 22-111) antibodyPDCD1LG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D5 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 33-236) antibodyPDCD1LG2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 40-75), (N-Term) antibodyPDCD1LG2 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 2011CT786-31-38 unconjugated
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应用备注
- Flow cytometry: 0.5-1 μg/million cells, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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说明
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Positive Control: Placenta or Pancreas. Thyroid Carcinoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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别名
- CD273
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背景
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Synonyms: B7 dendritic cell molecule, B7-DC, B7DC, Btdc, Butyrophilin B7DC, CD273, PD-L2, PDCD1L2, PDCD1LG2, PDL2, Programmed death ligand 2
Gene Symbol: PDCD1LG2
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分子量
- 31 kDa
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基因ID
- 80380
抗原
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