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Recombinant ADRP 抗体 (AA 249-376) (CF®405S)

This anti-ADRP antibody is a 兔 单克隆 antibody detecting ADRP in WB, IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7658551
发货至: 中国

Quick Overview for Recombinant ADRP 抗体 (AA 249-376) (CF®405S) (ABIN7658551)

抗原

See all ADRP (PLIN2) 抗体
ADRP (PLIN2) (Perilipin 2 (PLIN2))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This ADRP antibody is conjugated to CF®405S

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

ADFP-2755R
  • 抗原表位

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    AA 249-376

    原理

    Adipophilin / Perilipin-2 (Marker of Lipid Accumulation) (ADFP/2755R), CF405S conjugate

    产品特性

    Perilipin-2, also known as Adipophilin, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This 48 kDa protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (around aa 249-376) of human Adipophilin (ADFP) protein

    亚型

    IgG
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Western blotting 1-2 μg/mL. ELISA For coating, order Ab without BSA. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: HepG2 or JAR cells. Liver, Adrenal gland or Cerebellum.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    ADRP (PLIN2) (Perilipin 2 (PLIN2))

    别名

    Adipophilin

    背景

    Synonyms: Perilipin-2, Adipophilin, ADFP, ADRP, Adipose differentiation-related protein, Perilipin-2

    Gene Symbol: PLIN2

    分子量

    48 kDa

    基因ID

    123

    UniProt

    Q99541

    途径

    Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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