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PAX7 抗体 (AA 300-600) (CF®740)

This anti-PAX7 antibody is a 小鼠 单克隆 antibody detecting PAX7 in WB. Suitable for 人, 小鼠, 大鼠, 斑马鱼 和 小鸡.
产品编号 ABIN7658345
发货至: 中国

Quick Overview for PAX7 抗体 (AA 300-600) (CF®740) (ABIN7658345)

抗原

See all PAX7 抗体
PAX7 (Paired Box 7 (PAX7))

适用

  • 104
  • 65
  • 50
  • 17
  • 15
  • 8
  • 8
  • 7
  • 7
  • 4
  • 3
  • 3
  • 1
  • 1
人, 小鼠, 大鼠, 斑马鱼, 小鸡

宿主

  • 71
  • 37
  • 1
  • 1
小鼠

克隆类型

  • 63
  • 47
单克隆

标记

  • 53
  • 7
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PAX7 antibody is conjugated to CF®740

应用范围

  • 80
  • 33
  • 31
  • 30
  • 18
  • 15
  • 13
  • 13
  • 13
  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

PAX7-497
  • 抗原表位

    • 22
    • 16
    • 9
    • 9
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 300-600

    原理

    PAX7(PAX7/497), CF740 conjugate

    产品特性

    The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (aa300-600) of human PAX7 protein

    亚型

    IgG1, kappa
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology (frozen) 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: Rhabdomyosarcoma (RMS)|U2OS

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    PAX7 (Paired Box 7 (PAX7))

    别名

    PAX7

    背景

    Synonyms: HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2

    Gene Symbol: PAX7

    分子量

    57 kDa

    基因ID

    5081

    UniProt

    P23759
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