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Recombinant PAX5 抗体 (CF®405S)

This anti-PAX5 antibody is a 小鼠 单克隆 antibody detecting PAX5 in WB. Suitable for 人.
产品编号 ABIN7658286
发货至: 中国

Quick Overview for Recombinant PAX5 抗体 (CF®405S) (ABIN7658286)

抗原

See all PAX5 抗体
PAX5 (Paired Box 5 (PAX5))

抗体类型

Recombinant Antibody

适用

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宿主

  • 86
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小鼠

克隆类型

  • 93
  • 75
单克隆

标记

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This PAX5 antibody is conjugated to CF®405S

应用范围

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Western Blotting (WB)

克隆位点

RPAX5-2060
  • 原理

    PAX5 / BSAP (Early B-Cell Marker)(rPAX5/2060), CF405S conjugate

    产品特性

    The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19, 000, full-length human proteins. The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length humanPAX5 protein

    亚型

    IgG1, kappa
  • 应用备注

    ELISA: For coating, purchase antibody without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

    说明

    Positive Control: Daudi or Ramos cells. Tonsil, spleen, Lymph Nodeor Colon Carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    PAX5 (Paired Box 5 (PAX5))

    别名

    BSAP

    背景

    Synonyms: B cell lineage specific activator, BSAP, EBB-1, KLP, Paired box 5

    Gene Symbol: PAX5

    Tissue Expression: B-cells

    分子量

    42 kDa

    基因ID

    5079

    UniProt

    Q02548
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