P-Cadherin 抗体 (CF®740)
Quick Overview for P-Cadherin 抗体 (CF®740) (ABIN7658271)
抗原
See all P-Cadherin (CDH3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- P-Cadherin (CDH3) (6A9), CF740 conjugate
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产品特性
- This antibody recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- A431 trypsinized membranes
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亚型
- IgG1, kappa
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anti-P-Cadherin (CDH3) (AA 371-660) antibody
CDH3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (N-Term) antibodyCDH3 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 625-725) antibodyCDH3 适用: 人, 小鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 24-350) antibodyCDH3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (C-Term) antibodyCDH3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 117-360) antibodyCDH3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 1-829) antibodyCDH3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 1-829) antibodyCDH3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 187-236) antibodyCDH3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 612-626), (Middle Region) antibodyCDH3 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: A431 or PC-3 cells. Pancreas, Placenta or Prostate
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- P-Cadherin (CDH3)
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别名
- P-Cadherin
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背景
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Synonyms: Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin
Gene Symbol: CDH3
Tissue Expression: Epithelial cells
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分子量
- 116 kDa
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基因ID
- 1001
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UniProt
- P22223
抗原
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