NME2 抗体 (Biotin)
Quick Overview for NME2 抗体 (Biotin) (ABIN7658192)
抗原
See all NME2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis)(CPTC-NME2-2), Biotin conjugate
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产品特性
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human NME2 protein
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: PC3, A549, HeLa, Jurkat cells. Ubiquitously expressed in all tissues.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- NME2 (Nucleoside diphosphate kinase B (NME2))
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别名
- NDPK-B
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背景
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Synonyms: C myc purine binding transcription factor PUF, C-myc purine-binding transcription factor PUF, epididymis secretory sperm binding protein Li 155an, HEL-S-155an, Histidine protein kinase NDKB, , NDP kinase B, NDPKB, nm23-H2, NM23B, NME/NM23 nucleoside diphosphate kinase 2, nme2, Nucleoside diphosphate kinase B,
Gene Symbol: NME2
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分子量
- 17 kDa
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基因ID
- 4831
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UniProt
- P22392
抗原
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