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NME2 抗体 (CF®405S)

This CF®405S-conjugated 小鼠 单克隆 anti-NME2 antibody (Clone CPTC-NME2-2) specifically detects NME2 in WB, IHC 和 IHC (fp). The antibody is reactive with 人 samples.
产品编号 ABIN7658185
发货至: 中国
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Quick Overview for NME2 抗体 (CF®405S) (ABIN7658185)

抗原

See all NME2 抗体
NME2 (Nucleoside diphosphate kinase B (NME2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NME2 antibody is conjugated to CF®405S

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

CPTC-NME2-2
  • 原理

    NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis)(CPTC-NME2-2), CF405S conjugate

    产品特性

    The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human NME2 protein

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: PC3, A549, HeLa, Jurkat cells. Ubiquitously expressed in all tissues.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    NME2 (Nucleoside diphosphate kinase B (NME2))

    别名

    NDPK-B

    背景

    Synonyms: C myc purine binding transcription factor PUF, C-myc purine-binding transcription factor PUF, epididymis secretory sperm binding protein Li 155an, HEL-S-155an, Histidine protein kinase NDKB, , NDP kinase B, NDPKB, nm23-H2, NM23B, NME/NM23 nucleoside diphosphate kinase 2, nme2, Nucleoside diphosphate kinase B,

    Gene Symbol: NME2

    分子量

    17 kDa

    基因ID

    4831

    UniProt

    P22392
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