MYCN 抗体 (CF®488A)
Quick Overview for MYCN 抗体 (CF®488A) (ABIN7657687)
抗原
See all MYCN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- n-Myc (Neuroblastoma Marker)(NMYC-1), CF488A conjugate
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产品特性
- The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human n-Myc protein.
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亚型
- IgG2a, kappa
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anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 401-464) antibody
MYCN 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 168-267) antibodyMYCN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 337-464) antibodyMYCN 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A4E9 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-100) antibodyMYCN 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) antibodyMYCN 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) antibodyMYCN 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-464) antibodyMYCN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-100) antibodyMYCN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (C-Term) antibodyMYCN 适用: 人 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (Internal Region) antibodyMYCN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: 293T whole cell lysates or recombinant Human n-Myc protein.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
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别名
- n-Myc
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背景
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Synonyms: Class E basic helix-loop-helix protein 37 (bHLHe37), MODED, N-myc proto-oncogene protein, Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene, ODED, pp65/67, v myc (avian) myelocytomatosis viral related oncogene neuroblastoma derived
Gene Symbol: MYCN
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分子量
- 67 kDa
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基因ID
- 4613
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UniProt
- P04198
抗原
-
