Myofibroblast Marker 抗体 (CF®647)
The 小鼠 单克隆 anti-Myofibroblast Marker antibody is suitable to detect Myofibroblast Marker in samples from 人. It has been validated for WB.
产品编号 ABIN7657604
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Myofibroblast Marker 抗体 (CF®647) (ABIN7657604)
抗原
Myofibroblast Marker
适用
人
宿主
小鼠
克隆类型
单克隆
标记
CF®647
应用范围
Western Blotting (WB)
克隆位点
PR 2D3
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原理
- Myofibroblast Marker(PR 2D3), CF647 conjugate
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产品特性
- Myofibroblasts are a unique group of smooth muscle-like fibroblasts that play an important role in oncogenesis, inflammation, repair, wound contraction and fibrosis. Like smooth muscle (SM) cells, myofibroblasts contain microfilament bundles and express -SM Actin, the Actin isoform that is present in myoepithelial cells and SM cells and especially abundant in vascular SM cells. Myofibroblasts secrete inflammatory and anti-inflammatory cytokines, chemokines, growth factors and lipid and gaseous inflammatory mediators, as well as extracellular matrix proteins and proteases in most organs and tissues. Besides being temporarily present following tissue injuries and fibrocontractive diseases, myofibroblasts are also present under normal conditions in regions such as the skin, pulmonary septa and periodontal ligaments. Stem cell factor and platelet-derived growth factor (PDGF) are two secreted proteins responsible for differentiating myofibroblasts from embryological stem cells. PR 2D3 reacts with a cell membrane component of cells in the pericrypt sheath, with smooth muscle cells and myofibroblasts. This antibody is considered to be the gold standard for the identification of myofibroblasts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Crude homogenate of normal human colorectal mucosa
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亚型
- IgG1, kappa
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anti-Myofibroblast Marker antibody
适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PR 2D3 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Myofibroblasts.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Myofibroblast Marker
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背景
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Gene Symbol: Not Known
Tissue Expression: Myofibroblasts
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分子量
- 28 kDa
抗原
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