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MUC6 抗体 (CF®740)

This anti-MUC6 antibody is a 小鼠 单克隆 antibody detecting MUC6 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7657474
发货至: 中国

Quick Overview for MUC6 抗体 (CF®740) (ABIN7657474)

抗原

See all MUC6 抗体
MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC6 antibody is conjugated to CF®740

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

CLH5
  • 原理

    Mucin 6 (MUC6)(CLH5), CF740 conjugate

    产品特性

    The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    A synthetic peptide of the Gastric Mucin 6 tandem repeat sequence

    亚型

    IgG1, kappa
  • 应用备注

    Immunohistology formalin-fixed 2-4 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Immunofluorescence 1-2 μg/mL. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: Stomach

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

    别名

    Mucin 6

    背景

    Synonyms: Gastric mucin 6, MUC6, MUC6 mucin, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6

    Gene Symbol: MUC6

    Tissue Expression: Epithelial cells|Gall bladder|Intestine|Stomach

    分子量

    252 kDa

    基因ID

    4588

    UniProt

    Q6W4X9
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